Posts tagged controlling HIV

New Imagery of HIV

New Imagery of HIV: Electron Microscope Allows Up Close View of HIV Function

Research on how HIV works, infects cells, and responds to various forms of treatment, has now been ongoing for about three decades. Important information has been collected and better understood over the years, which has led to a series of advancements against the disease. The benefits of this research can be seen by the number of patients who are now able to not only enjoy a fairly normal lifestyle, but who also reach an almost average life expectancy. These are certainly great statistics that reflect the strides made against the disease. However, new imagery of HIV in action could revolutionize not only how research is done, but also allow insight into the best ways of how to continue fighting the epidemic.

A team of medical researchers recently used electron microscopy to view a 3D image of HIV in the digestive tract. This exciting step allowed the researchers to study the infection up close and live. Because of this ability to actually watch the virus in real-time, we now have greater insight into how HIV works and, thus, how it may be stopped.

Examining the infected tissue in this way, which gave scientists the opportunity to track both how human cells respond to the virus, and monitor how HIV itself functions, has given scientists a new understanding of the disease. The team could view concentrated areas in the gut where HIV pooled, leading to a greater appreciation of how the virus spreads and invades healthy tissue.

Another interesting observation involves our immune system. HIV appears to hide in the deep sections of the digestive tract, an area known to be associated with immune activity. Researchers believe an antibody attack using drugs could prove effective against wiping out these clusters of HIV. If so, this could have a massive impact on slowing further infection.

Seeing HIV live in infected tissue gives hope that more discoveries await on how this vicious virus functions. As with the new imagery of HIV from electron microscope imagery, new understanding of how the disease functions will almost certainly lead to even more effective ways of dealing with it. Researchers are hoping to continue to use electron microscopy to view other particulars of the infection and to monitor how it functions in those areas, as well. Thanks to the new imagery of HIV, and tracking how the HIV infection gains a foothold and grows, means that we are one step closer to closing the chapter on HIV.

 

 

Study May Result in HIV Treatment for Millions

A landmark study has shown that a smaller dose of HIV treatments is just as effective at suppressing HIV as the standard dose currently used. These findings may benefit millions of individuals who have never been able to receive treatment due to the expensive price of the drugs. Knowing that a smaller dose is sufficient may open the way for millions to receive the necessary treatments to control this disease for the first time.

Lower doses equal lower costs. Lower costs mean that current budgets for providing healthcare to HIV patients in developing nations will go further by reaching more patients. The study was conducted using people who are HIV positive from thirteen different countries. Individuals who could never have afforded treatment were able to get a reduced dose or a full dose as a part of the study. Half of the patients were given the standard dose, while the other half only took two-thirds of the standard treatment amount.

Over 600 individuals took part in the study altogether. After a year of treatment and observation, it became clear that reducing the treatment by one-third did not have any detrimental results for the patients. This is a huge revelation for the treatment of HIV in developing nations where the primary issue has always been cost of treatment.

As with many HIV research studies, this study was funded by a foundation set up by Bill Gates and his wife, Melinda. Gates’ donations, to the tune of tens of millions of dollars, have been instrumental in continuing research and helping HIV-positive individuals receive the best care possible across the globe.

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